Bibliography

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2010

  1. Validation of a Blood-Based Laboratory Test to Aid in the Confirmation of a Diagnosis of Schizophrenia. 2010. Emanuel Schwarz1, Rauf Izmailov2, Michael Spain2, Anthony Barnes2, James P. Mapes2, Paul C.Guest1, Hassan Rahmoune1, Sandra Pietsch1, F. Markus Leweke3,4, Matthias Rothermundt5, Johann Steiner6, Dagmar Koethe3, Laura Kranaster3,4, Patricia Ohrmann5, Thomas Suslow5, Yishai Levin1, Bernhard Bogerts6, Nico (JM) van Beveren7, George McAllister8, Natalya Weber9, David Niebuhr9, David Cowan9, Robert H. Yolken10 and Sabine Bahn1. 1Institute of Biotechnology, University of Cambridge, Cambridge, UK. 2Rules-Based Medicine, Inc., Austin, Texas. 3Dept of Psychiatry and Psychotherapy, University of Cologne, Germany. 4Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany. 5Department of Psychiatry, University of Muenster, Germany. 6Department of Psychiatry, University of Magdeburg, Germany. 7Department of Psychiatry, Erasmus University, Medical Center, Rotterdam, Netherlands. 8Psynova Neurotech Ltd, Cambridge, UK. 9Walter Reed Army Institute of Research, Silver Spring, MD. 10The Stanley Medical Research Institute, Chevy Chase, MD. Biomarker Insights 2010:5 39–47.
  2. Lack of a Major Role of Staphylococcus aureus Panton-Valentine Leukocidin in Lower Respiratory Tract Infection in Nonhuman Primates. 2010. Olsen1 RJ, Kobayashi1 SD, Ayeras1 AA, Ashraf1 M, Graves2 SF, Ragasa1 W, Humbird3 T, Greaver3 JL, Cantu1 C, Swain2 JL, Jenkins4 L, Blasdel3 T, Cagle1 PT, Gardner1 DJ, DeLeo2 FR, Musser1 JM. 1The Methodist Hospital, Houston, TX; 2Rocky Moujntain Laboratories, NIAID, NIH, Hamilton, MT; 3University of Houston, TX; 4Baylor College of Medicine, Houston, TX. American Journal of Pathology 176(3) 1346-1354.
  3. Insight in Modulation of Inflammation in Response to Diclofenac Intervention: a Human Intervention Study. 2010. Marjan J van Erk1, Suzan Wopereis1, Carina Rubingh1, Trinette van Vliet1, Elwin Verheij1, Nicole HP Cnubben1, Theresa L Pedersen2, John W Newman 2,3, Age K Smilde1, Jan van der Greef1, Henk FJ Hendriks1, Ben van Ommen. 1TNO Quality of Life, the Netherlands. 2USDA, Davis, CA, 3University of California, Davis. BMC Medical Genomics 2010, 3-5, online.
  4. Kidney Injury Molecule-1 Outperforms Traditional Biomarkers of Kidney Injury in Preclinical Biomarker Qualification Studies. 2010. Vishal S Vaidya1, Josef S Ozer 2, Frank Dieterle3, Fitz B Collings1, Victoria Ramirez1, Sean Troth2, Nagaraja Muniappa2, Douglas Thudium2, David Gerhold2, Daniel J Holder2, Norma A Bobadilla4, Estelle Marrer3, Elias Perentes3, André Cordier3, Jacky Vonderscher3, Gérard Maurer3, Peter L Goering5, Frank D Sistare2 & Joseph V Bonventre1. 1Harvard Medical School, Boston, MA, 2Merck, West Point, PA. 3Novartis, Basel, Switzerland. 4 Universidad Nacional Autónoma de México and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico. 5 Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MA. Nature Biotechnology 28 (5) 478-488.
  5. Proteomics Study of Plasma Biomarkers. 2010. Todd M. Umstead, Chia-jung K. Lu, Willard M. Freeman, John L. Myers, J. Brian Clark, Neal J. Thomas, Vernon M. Chinchilli, Kent E. Vrana, Akif Ündar and David S. Phelps. Pennsylvania State University College of Medicine, Hershey, PA. Pediatric Research, 18 March 2010, online.
  6. Hypercoagulability, Platelet Function, Inflammation and Coronary Artery Disease Acuity: Results of the Thrombotic RIsk Progression (TRIP) Study. 2010. Udaya Tantry, Kevin Bliden, Thomas Suarez, Rolf Kreutz, Joseph Dichiara, Paul Gurbel. Sinai Center for Thrombosis Research, Baltimore, MA. Platelets, 2010, 1-8, online.
  7. Feasibility of FDG Imaging of the Coronary Arteries - Comparison Between Acute Coronary Syndrome and Stable Angina. 2010. Ian S. Rogers, Khurram Nasir, Amparo L. Figueroa, Ricardo C. Cury, Udo Hoffmann, David A. Vermylen, Thomas J. Brady, Ahmed Tawakol, Cardiac MR PET CT Program, Division of Cardiology and Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA. JACC: Cardiovascular Imaging, 3(4), 388-397.
  8. Identification of Breast Cancer Biomarkers in Transgenic Mouse Models: a Proteomics Approach. 2010. Wendy Rodenburg1, Jeroen L.A. Pennings1, Conny T.M. van Oostrom1, Marianne Roodbergen1, Raoul V Kuiper1,2, Mirjam Luijten1, and Annemieke de Vries1. 1Laboratory for Health Protection Research, National Institute of Public Health and the Environment, Bilthoven, The Netherlands; 2 Dutch Molecular Pathology Centre, Utrecht University, Utrecht, the Netherlands. Proteomics – Clinical Applications 24 Mar 2010, online.
  9. How Informatics Can Potentiate Precompetitive Open-Source Collaboration to Jump-Start Drug Discovery and Development. 2010. ED Perakslis, J Van Dam and S Szalma. Centocor R&D, Inc., Radnor, PA. Clinical Pharmacology & Therapeutics 87 (5), 614-616.
  10. A Panel of Urinary Biomarkers to Monitor Reversibility of Renal Injury and a Serum Marker with Improved Potential to Assess Renal Function. 2010. Josef S Ozer1, Frank Dieterle2, Sean Troth1, Elias Perentes2, André Cordier2, Pablo Verdes2, Frank Staedtler2, Andreas Mahl2, Olivier Grenet2, Daniel R Roth2, Daniel Wahl2, François Legay2, Daniel Holder1, Zoltan Erdos1, Katerina Vlasakova1, Hong Jin1, Yan Yu1, Nagaraja Muniappa1, Tom Forest1, Holly K Clouse1, Spencer Reynolds1, Wendy J Bailey1, Douglas T Thudium1, Michael J Topper1, Thomas R Skopek1, Joseph F Sina1, Warren E Glaab1, Jacky Vonderscher2, Gérard Maurer2, Salah-Dine Chibout2, Frank D Sistare1 & David L Gerhold.1 1Merck Research Laboratories, West Point, PA; 2 Novartis, Basel, Switzerland. Nature Biotechnology 28(5) 486-494.
  11. A Guidance for Renal Biomarker Lead Optimization and Use in Translational Pharmacodynamics. 2010. Josef S. Ozer. Pfizer Global Research and Development, Pharmacokinetics, Dynamics, and Metabolism, St Louis, MO. Drug Discovery Today 15(3/4) 142-147, Feb 2010.
  12. Decreased C-Reactive Protein Levels in Alzheimer Disease. 2010. Sid E. O’Bryant,1 Stephen C. Waring,2 Valerie Hobson,3 James R. Hall,4 Carol B. Moore,5 Teodoro Bottiglieri,6 Paul Massman,7,8 and Ramon Diaz-Arrastia5. 1Texas Tech University Health Sciences Center, Lubbock, TX; 2Marshfield Clinic Research Foundation, Epidemiology Research Center, Marshfield, Wisconsin; 3Department of Psychology, Texas Tech University, Lubbock, TX; 4Department of Psychiatry, University of North Texas Health Science Center, Fort Worth, TX; 5Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX; 6Institute for Metabolic Disease, Baylor University Medical Center, Dallas, TX; 7Department of Neurology, Baylor College of Medicine, Houston, TX; 8 Department of Psychology, University of Houston, Houston, TX. Journal of Geriatric Psychiatry and Neurology 23(1) 49-53.
  13. Aged Mice Display an Altered Pulmonary Host Response to Francisella Tularensis Live Vaccine Strain (LVS) infections. 2010. C.A. Mares, S.S. Ojeda, Q. Li, E.G. Morris, J.J. Coalson, J.M. Teale. The University of Texas Health Science Center at San Antonio. Experimental Gerontology 45; 91–96.
  14. Comparative Efficacy and Safety of Aliskiren and Irbesartan in Patients with Hypertension and Metabolic Syndrome. 2010. W Krone1, M Hanefeld2, H-F Meyer3, T Jung4, M Bartlett5, C-M Yeh6, I Rajman5, MF Prescott6 and WP Dole7. 1Klinik II und Poliklinik fu¨r Innere Medizin, Zentrum fu¨r Molekulare Medizin der Universita¨t zu Ko¨ln, Cologne, Germany; 2Centre for Clinical Studies, GWT-TUD GmbH, Dresden, Germany; 3Facharzt fu¨r Allgemeinmedizin, Marl, Germany; 4Facharzt fu¨r Allgemeinmedizin, Deggingen, Germany; 5Novartis Institutes for Biomedical Research, Basel, Switzerland; 6Novartis Pharmaceuticals Corporation, East Hanover, NJ; 7 Novartis Institutes for Biomedical Research Inc., Cambridge, MA. Journal of Human Hypertension 8 April 2010, online.
  15. Novel CSF Biomarkers for Alzheimer’s Disease and Mild Cognitive Impairment. 2010. William T. Hu, Alice Chen-Plotkin, Steven E. Arnold, Murray Grossman, Christopher M. Clark, Leslie M. Shaw, Eve Pickering, Max Kuhn, Yu Chen, Leo McCluskey, Lauren Elman, Jason Karlawish, Howard I. Hurtig, Andrew Siderowf, Virginia M.-Y. Lee, Holly Soares, John Q. Trojanowski. University of Pennsylvania School of Medicine, Philadelphia, PA. Acta Neuropathologica 119:669-678, 16 March 2010, online.
  16. Systemic Levels of G-CSF and Interleukin-6 Determine the Angiogenic Potential of Bone Marrow Resident Monocytes. 2010. Alyssa D. Gregory, Benjamin J. Capoccia, Jill R. Woloszynek, and Daniel C. Link. Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri. Journal of Leukocyte Biology, 1 April 2010, online.
  17. Defining the Optimal Biological Dose of NGR-hTNF, a Selective Vascular Targeting Agent, in Advanced Solid Tumours. 2010. Vanesa Gregorc1, Giovanni Citterio1, Giordano Vitali1, Anna Spreafico1, Paola Scifo1, Anna Borri1, Giovanni Donadoni1, Gilda Rossoni1, Angelo Corti1, Federico Caligaris-Cappi1, 3, Alessandro Del Maschio1, 3, Antonio Esposito1, Francesco De Cobelli1, Flavio Dell’Acqua1, Antonella Troysi4, Paolo Bruzzi2, Antonio Lambiase4, Claudio Bordignon 3, 4, 1Istituto Scientifico San Raffaele, Milan, Italy 2Clinical Epidemiology Unit, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy 3Universita` Vita-Salute San Raffaele, Milan, Italy 4MolMed, Milan, Italy. European Journal of Cancer 46;198–206
  18. Interleukin-15 Enhances Proliferation and Chemokine Secretion of Human Follicular Dendritic Cells. 2010. Minchan Gil,1 Seo-Jeong Park,1 Yoo-Sam Chung2 and Chan-Sik Park.1 1Departments of Pathology and 2 Otolaryngology, Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Korea. Immunology, 16 March 2010, online.
  19. The Transcriptome of Nrf2-/- Mice Provides Evidence for Impaired Cell Cycle Progression in the Development of Cigarette Smoke–Induced Emphysematous Changes. 2010. Stephan Gebel,1 Svenja Diehl,1 Jan Pype,2 Barbel Friedrichs, 1 Horst Weiler, 1 Jutta Schuller, 1 Haiyan Xu, 2 Keiko Taguchi,3 Masayuki Yamamoto,3 and Thomas Muller1, 1Philip Morris Research Laboratories, Koln, Germany; 2Philip Morris Research Laboratories bvba, Leuven, Belgium; and 3Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Japan. Toxicological Sciences, 115(1):238-252.
  20. Classification of Alcohol Abuse by Plasma Protein Biomarkers. 2010. Willard M. Freeman, Anna C. Salzberg, Steven W. Gonzales, Kathleen A. Grant, and Kent E. Vrana. Department of Pharmacology (WMF, KEV), Penn State College of Medicine; Penn State Hershey Cancer Institute (ACS), Hershey, Pennsylvania; Biotic Micro (SWG), Clemmons, North Carolina; and the Division of Neuroscience (KAG), Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon. Biological Psychiatry, 17 March 2010, online.
  21. Human Cytokine Response to Texas Crotaline Envenomation Before and After Antivenom Administration. 2010. Patrick Crocker DOa, Omid Zad MDb, Truman Milling MDb,*, Todd Maxson MDa, Benjamin Kingb, Elbert Whorton PhDc . aDell Children's Medical Center of Central Texas, bUniversity Medical Center at Brackenridge, c University of Texas Medical Branch. The American Journal of Emergency Medicine, 25 March 2010, online.
  22. Uromodulin Levels Associate with a Common UMOD Variant and Risk for Incident CKD. 2010. Anna Köttgen,1 Caroline S. Fox,2 et. al. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MA; 2 Brigham and Women’s Hospital and Harvard Medical School, Boston, MA. Journal of the American Society of Nephrology, 21: 337–344.
  23. Dysregulated Macrophage-Inflammatory Protein-2 Expression Drives Illness in Bacterial Superinfection of Influenza. 2010. C. Zavitz,1 C. Bauer,1 G. Gaschler,1 K. Fraser,1 R. Strieter,2 C. Hogaboam,3 and M. Stampfli1. 1 McMaster University, Hamilton, Ontario, Canada; 2University of Virginia, Charlottesville, VA; and 3University of Michigan Medical School, Ann Arbor, MI. The Journal of Immunology, 184, 2001-2013.
  24. Plasma Protein Biomarkers for Depression and Schizophrenia by Multi Analyte Profiling of Case-Control Collections. 2010. Enrico Domenici1, David R. Wille1, Federica Tozzi1, Inga Prokopenko1, Sam Miller1, Astrid McKeown1, Claire Brittain1, Dan Rujescu2, Ina Giegling2, Christoph W. Turck3, Florian Holsboer 3, Edward T. Bullmore1,4, Lefkos Middleton1, Emilio Merlo-Pich1, Robert C. Alexander1, Pierandrea Muglia1. 1GlaxoSmithKline 2Ludwig-Maximilians-University, Munich, Germany, 3 Max-Planck Institute of Psychiatry, Munich, Germany, University of Cambridge, Cambridge, UK, PLoS ONE 5(2): e9166.
  25. Interleukin-8 Mediates Resistance to Antiangiogenic Agent Sunitinib in Renal Cell Carcinoma. 2010. Dan Huang1, Yan Ding1, Ming Zhou3, Brian I. Rini4, David Petillo1, Chao-Nan Qian1,5, Richard Kahnoski6, P. Andrew Futreal7, Kyle A. Furge2, and Bin Tean Teh1. 1Laboratory of Cancer Genetics, 2Laboratory of Computational Biology, Van Andel Research Institute, Grand Rapids, Michigan; Departments of 3Anatomic Pathology and 4Solid Tumor Oncology and Urology, Cleveland Clinic, Cleveland, Ohio; 5The State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, People's Republic of China; 6Department of Urology, Spectrum Health, Grand Rapids, Michigan; and 7 Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom. Cancer Research, 70(3).
  26. Identification of Targeted Analyte Clusters for Studies of Schizophrenia. 2010. Cheng, Tammy M. K.1, Lu, Yu-En2, Guest, Paul C.1, Rahmoune,Hassan1, Harris, Laura W.1, Wang, Lan, Ma, Dan1, Stelzhammer, Victoria1, Umrania, Yagnesh1, Wayland, Matt T.1, Lio, Pietro2 and Bahn, Sabine1. 1Department of Chemical Engineering and Biotechnology; 2 Department of Computer Laboratory, University of Cambridge, Cambridge, United Kingdom. Molecular and Cellular Proteomics, 9:510-522.
  27. Quantitative Multiplexed Patterning of Immune-related Biomarkers. 2010. Dominic Eisinger, Ralph McDade, and Thomas Joos. Rules-Based Medicine, Austin, Texas. Biomarkers in Drug Development: A Handbook of Practice, Application, and Strategy. Ch. 6, p. 121-134.
  28. Identification of Distinct Plasma Biomarker Signatures in Patients with Rapid and Slow Declining Forms of COPD. 2010. Viswanath Devanarayan1, Mary-Beth Scholand2, John Hoidal2, Mark F. Leppert3, Michael A. Crackower4, Gary P. O’Neill4, and Francois G. Gervais.4 1Experimental Medicine Statistics, Merck & Co., PA 2Department of Internal Medicine, University of Utah, Salt Lake City, Utah; 3Department of Human Genetics, University of Utah, Salt Lake City, Utah, 4Department of Biochemistry and Molecular Biology, Merck Frosst Centre for Therapeutic Research, Kirkland, Quebec, Canada. COPD: Journal of Chronic Obstructive Pulmonary Disease, 7:51–58
  29. Protein Microarrays for Personalized Medicine. 2010. Xiaobo Yu, Nicole Schneiderhan-Marra, and Thomas O. Joos. NMI Natural and Medical Sciences Institute, University of Tuebingen, Reutlingen, Germany. Clinical Chemistry 56: 376-387.
  30. Plasma Biomarkers in Carbon Monoxide Poisoning. 2010. Stephen R. Thom1,2, Veena M. Bhopale1, Tatyana M. Milovanova1, Kevin R. Hardy1,2, Christopher J. Logue1,2, David S. Lambert1,2, Andrea B. Troxel3, Karri Ballard4, and Dominic Eisinger4. 1Department of Emergency Medicine, University of Pennsylvania, Philadelphia, PA. 2Institute for Environmental Medicine, University of Pennsylvania, Philadelphia, PA. 3Department of Biostatistics & Epidemiology, University of Pennsylvania, Philadelphia, PA. 4 Rules Based Medicine, Inc., Austin, TX. Clinical Toxicology January, Vol. 48, No. 1, p. 47-56.

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2009

  1. RelB Is Differentially Regulated by IκB Kinase-α in B Cells and Mouse Lung by Cigarette Smoke. 2009.Se-Ran Yang, Hongwei Yao, Saravanan Rajendrasozhan, Sangwoon Chung, Indika Edirisinghe, Samantha Valvo, George Fromm, Michael J. McCabe Jr., Patricia J. Sime, Richard P. Phipps, Jian-Dong Li, Michael Bulger, and Irfan Rahman. University of Rochester Medical Center, Rochester, NY. American Journal of Respiratory and Cell Molecular Biology 2009 Feb; 40(2): 147-58.
  2. Heterosubtypic Anti-avian H5N1 Influenza antibodies in Intravenous Immunoglobulins from Globally Separate Populations Protect Against H5N1 Infection in Cell Culture. 2009. John S Sullivan1,2, Paul W Selleck3, Teena Downton1, Ingrid Boehm2,4, Anna-Maree Axell3, Yasmin Ayob5, Natalie M Kapitza1, Wayne Dyer4, Anna Fitzgerald6, Bradley Walsh6 and Garry W Lynch1,7,8. 1Biosafety, Immunobiology, Global Health and Pandemic Infections Research, The University of Sydney, Australia,2Children's Cancer Institute Australia for Medical Research, Australia, 3The Australian Animal Health Laboratories, Australia, 4The Australian Red Cross Blood Service, Sydney, Australia, 5The National Blood Centre, Kuala Lumpur, Malaysia, 6Minomic Pty Ltd, Australia, 7Faculty of Veterinary Science, The University of Sydney, 8 Faculty of Dentistry, University of Sydney, Australia. Journal of Molecular and Genetic Medicine, 3(2), 217-224.
  3. Distinct Functions of Activated Protein C Differentially Attenuate Acute Kidney Injury. 2009. Akanksha Gupta,1 Bruce Gerlitz,1 Mark A. Richardson,1 Christopher Bull,1 David T. Berg,1 Samreen Syed,1 Elizabeth J. Galbreath,1 Barbara A. Swanson,2 Bryan E. Jones,1 and Brian W. Grinnell.1 1Lilly Research Laboratories, Indianapolis, Indiana; and 2 Applied Molecular Evolution, San Diego, California. Journal of the American Society of Nephrology, 20: 267–277.
  4. Perturbation of Mouse Retinal Vascular Morphogenesis by Anthrax Lethal Toxin. 2009. Jennifer L. Bromberg-White, Elissa Boguslawski, Nicholas S. Duesbery Laboratory of Cancer and Developmental Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan. PLoS ONE 4(9):e6956.
  5. Pathway Focused Protein Profiling Indicates Differential Function for IL-1B, -18 and VEGF During Initiation and Resolution of Lung Inflammation Evoked by Carbon Nanoparticle Exposure in Mice. 2009. Koustav Ganguly1, Swapna Upadhyay1, Martin Irmler2, Shinji Takenaka1, Katrin Pukelsheim1, Johannes Beckers2,3, Eckard Hamelmann4,5, Holger Schulz†1 and Tobias Stoeger†1. 1Comprehensive Pneumology Center, Institute of Lung Biology and Disease, München, German Research Center for Environmental Health, Neuherberg/Munich, Germany, 2Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg/Munich, Germany, 3 Center of Life and Food Sciences, Technical University Munich, Freising, 85354, Germany, Charité Universitätsmedizin Berlin, Germany and Ruhr-University Bochum, Germany. Particle and Fibre Toxicology, 6:31.
  6. Value of New Biomarkers for Safety Testing in Drug Development. 2009. Philip Hewitt and Thomas Herget. Merck, Darmstadt, Germany. Expert Review of Molecular Diagnostics, Sep;9(6):531-5366.
  7. A Saturated Fatty Acid–rich Diet Induces an Obesity-linked Proinflammatory Gene Eexpression Profile in Adipose Tissue of Subjects at Risk of Metabolic Syndrome. 2009. Susan J van Dijk, Edith JM Feskens, Marieke B Bos, Dianne WM Hoelen, Rik Heijligenberg, Mechteld Grootte Bromhaar, Lisette CPGM de Groot, Jeanne HM de Vries, Michael Muller, and Lydia A Afman. The Division of Human Nutrition, Wageningen University, Netherlands (SJvD, EJMF, MBB, MGB, LCPGMdG, JHMdV, MM, and LAA); the Department of Internal Medicine, Hospital Gelderse Vallei, Ede, Netherlands (DWMH and RH); and the Netherlands Nutrigenomics Consortium, TI Food and Nutrition, Wageningen, Netherlands (MGB, MM, and LAA). American Journal Clinical Nutrition; 90:1656–64.
  8. Bacteria Challenge in Smoke-exposed Mice Exacerbates Inflammation and Skews the Inflammatory Profile. 2009. Gordon J. Gaschler1, Marko Skrtic2, Caleb C. J. Zavitz1, Maria Lindahl3, Per-Ola Onnervik3, Timothy F. Murphy4, Sanjay Sethi4, and Martin R. Stampfli2,5. 1Medical Sciences Graduate Program, 2Department of Pathology and Molecular Medicine, Centre for Gene Therapeutics, and 5Department of Medicine, McMaster University, Hamilton, Ontario, Canada; 3AstraZeneca, Lund, Sweden; and 4 Department of Medicine, University at Buffalo, State University of New York, Buffalo, New York. American Journal of Respiratory and Critical Care Medicine, Vol 179, p. 1-10.
  9. Western-Style Diets Induce Oxidative Stress and Dysregulate Immune Responses in the Colon in a Mouse Model of Sporadic Colon Cancer. 2009. Ildiko Erdelyi,1 Natasha Levenkova,2 Elaine Y. Lin,3 John T. Pinto,4 Martin Lipkin,1 Fred W. Quimby,5 and Peter R. Holt6. 1Department of Medicine, Weill Cornell Medical College, New York, NY 10021; 2Hospital Informatics, 5Laboratory Animal Research Center, and 6Laboratory of Biochemical Genetics and Metabolism, The Rockefeller University, New York, NY 10065; 3Department of Medicine, Montefiore Medical Center, Albert Einstein Cancer Center, Albert Einstein College of Medicine, New York, NY; and 4 Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY. Journal of Nutrition 139:2072-2078.
  10. Analysis of Renal Biomarkers in Samples of Rat Urine Samples Frozen for 44 months From a Study on Puromycin Amino Nucleoside (PAN). 2009. Marie-France Perron1, Roger Burnett1, Alexandre Reiniche1, Jean-Paul Briffaux1, Dominic Eisinger2, Sabine Küsters2, and James Mapes2. 1MDS Pharma Services, L’Arbresle, France; Toxicology Letters. Volume 189, Supplement 1, S159.
  11. High Content Analysis of Human Fibroblast Cell Cultures after Exposure to Space Radiation. 2009. Birger Dieriks,a,1 Winnok De Vos,a,1 Geert Meesen,a Kaat Van Oostveldt,a Tim De Meyer,b Myriam Ghardi,c Sarah Baatoutc and Patrick Van Oostveldta,2 . aLaboratory for Bio-Imaging and Molecular Cytology and bLaboratory for Bioinformatics and Computational Genomics, Department of Molecular Biotechnology, Ghent University, Gent, Belgium; and c Laboratory Molecular & Cellular Biology, Radiobiology Unit, Belgian Nuclear Research Center, Mol, Belgium. Radiation Research, 172, 423-436.
  12. The Multiplex Bead Array Approach to Identifying Serum Biomarkers Associated with Breast Cancer. 2009. Byoung Kwon Kim1, Jong Won Lee2, Pil Je Park2, Yong Sung Shin2, Won Young Lee2, Kyung Ae Lee2, Sena Ye2, Heesun Hyun2, Kyung Nam Kang2, Donghwa Yeo2, Youngdai Kim2, Sung Yup Ohn3, Dong Young Noh2 and Chul Woo Kim2. 1Department of Laboratory Medicine and Pathology, The Armed Forces Capital Hospital, Sungnam City,Korea; 2 Seoul National University, Seoul, Korea; 3 Korea Aerospace University, Gyeonggi-do, Korea; Breast Cancer Research; 11-R22, online.
  13. Identifying Early Markers of Alzheimer's Disease Using Quantitative Multiplex Proteomic Immunoassay Panels. 2009. Holly D. Soares1, Yu Chen1, Marwin Sabbagh2, Alex Rohrer2, Elisabeth Schrijvers3, Monique Breteler3. 1Pfizer Global Research and Development, Groton, Connecticut; 2 Sun Health Research Institute, Sun City, Arizona; 3Erasmus University, Rotterdam, the Netherlands. Biomarkers in Brain Disease: Annals of the New York Academy of Sciences; Volume 1180: 56-67.
  14. Growth Characteristics of the Nonhuman Primate Embryonic Stem Cell Line Cjes001 Depending on Feeder Cell Treatment. 2009. Gesine Fleischmann1, Thomas Muller2, Rainer Blasczyk2, Erika Sasaki3,4, and Peter A. Horn1. 1Institute for Transfusion Medicine, University Hospital Essen, Essen, Germany; 2Institute for Transfusion Medicine, Hannover Medical School, Hannover, Germany; 3Central Institute for Experimental Animals, Laboratory of Applied Developmental Biology, Department of Marmoset Research, Kawasaki, Japan; 4Center for Human Metabolomic System Biology, School of Medicine, Keio University, Tokyo, Japan. Cloning and Stem Cells. Volume 11, Number 2; 225-233.
  15. Chronic Treatment with Clenbuterol Modulates Endothelial Progenitor Cells and Circulating Factors in a Murine Model of Cardiomyopathy. 2009. James E. Rider1, Sean P. Polster1, Sangjin Lee1, Nathan J. Charles1, Neeta Adhikari1, Ami Mariash1, George Tadros1, Jenna Stangland1, Ryszard T. Smolenski2, Cesare M Terracciano2, Paul J.R. Barton2, Emma J. Birks2, Magdi H. Yacoub2, Leslie W. Miller3, Jennifer L. Hall1. 1Lillehei Heart Institute, University of Minnesota, Minneapolis, MN; 2Heart Science Centre, National Heart and Lung Institute, Imperial College London; 3Washington Hospital Center and Georgetown University, Washington, DC. Journal of Cardiovascular Translational Research. 2:182–190.
  16. Brain-Derived Neurotrophic Factor Levels in Alzheimer’s Disease. 2009. Sid E. O’Bryanta, Valerie Hobsonb, James R. Hallc, Stephen C. Waringd, Wenyan Chane,Paul Massmanf,g, Laura Lacritzh, C. Munro Cullumh,i and Ramon Diaz-Arrastiai for the Texas Alzheimer’s Research Consortium1. aDepartment of Neurology, Texas Tech University Health Sciences Center, Lubbock, TX; bDepartment of Psychology, Texas Tech University Health Sciences Center, Lubbock, TX; cDepartment of Psychiatry, University of North Texas Health Science Center, Fort Worth, TX; dUniversity of Texas Health Science Center, Division of Epidemiology, Houston, TX; eUniversity of Texas Health Science Center, Division of Biostatistics, Houston, TX; fDepartment of Neurology, Baylor College of Medicine, Houston, TX; gDepartment of Psychology University of Houston, Houston, TX; hDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX; iDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, TX; Journal of Alzheimer’s Disease. 17:337–341.
  17. A Novel ENU-induced Mutation, Peewee, Causes Dwarfism in the Mouse. 2009. Lee Bokryeon1, Kiyoshi Kano1, Jay Young2, Simon W. M. John2, Patsy M. Nishina2, Jurgen K. Naggert2, Kunihiko Naito1. 1Laboratory of Applied Genetics, Graduate School of Agricultural and Life Science, University of Tokyo, Tokyo, Japan; 2 The Jackson Laboratory, Bar Harbor, ME. Mammalian Genome. 20:404-413.
  18. Matrix Metalloproteinases During and Outside of Migraine Attacks Without Aura. 2009. M Ashina 1 , JF Tvedskov 1 , K Lipka 1 , J Bilello 2,3 , M Penkowa 4 & J Olesen 1. 1 Danish Headache Centre and Department of Neurology, Glostrup Hospital and 4 Section of Neuroprotection, The Panum Institute, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, 2 GlaxoSmithKline R&D, Research Triangle Park and 3 Precision Human Biolaboratory, Durham, NC, USA. Cephalalgia, online.
  19. Molecular Analyte Profiling of the Early Events and Tissue Conditioning Following Intravesical Bacillus Calmette-Guerin Therapy in Patients With Superficial Bladder Cancer. 2009. l. Bisiaux, N. Thiounn, M.-O. Timsit, A. Eladaoui, H.-H. Chang, J. Mapes, A.S. Mogenet, J.-L. Bresson, D. Prié, S.P. Béchet, C. Baron, C. Sadorge, S.P. Thomas, E.B. Albert, P.S. Albert, M.L. Albert. Laboratoire d’Immunobiologie des Cellules Dendritiques, Department of Immunology (AB, HHC, ST, MLA) and Centre de Recherche Vaccinale et Biomédicale (SB, CB, CS), Institut Pasteur, INSERM U818 (AB, HHC, ST, MLA), Service d’Urologie (NT, MOT) and Service des Explorations Fonctionnelles, INSERM U845 (DP), Université René Descartes, Hôpital Necker, Centre d’Investigation Clinique AP-HP/INSERM (AE, AM, JLB), Université René Descartes, Paris, France, Rules Based Medicine, Inc., Austin, Texas (JM), and Staten Island Urological, Staten Island, New York (EBA, PSA). The Journal Of Urology. 181, 1571-1580.
  20. Immune Activation in Advanced Cancer Patients Treated with Recombinant IL-21: Multianalyte Profiling of Serum Proteins. 2009. M. G. Dodds1, K. S. Frederiksen2, K. Skak2, L. T. Hansen2, D. Lundsgaard2, J. A. Thompson3, S. D. Hughes1. 1Preclinical Development, ZymoGenetics, Seattle, WA; 2Novo Nordisk A/S, Copenhagen, Denmark; 3University of Washington, Seattle, WA. Cancer Immunology, Immunotherapy. 58, 843-854.
  21. A Multianalyte Profile of Serum Proteins to Screen for Toxicological Effects of Anticholinesterase Insecticides in the Rat. 2009. J. Gordon1, W. O. Ward2. 1Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711; 2Environmental Carcinogenesis Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC. NeuroToxicology. 30, 377-381.
  22. Strain-Dependent Increases in Retinal Inflammatory Proteins and Photoreceptor FGF-2 Expression in Streptozotocin-Induced Diabetic Rats. 2009. Stefanie J. Kirwin1, Suzanne T. Kanaly2, Noelle A. Linke2, Jeffrey L. Edelman1. Department of Biological Sciences, Allergan, Inc., Irvine, California; 2 Department of Pathology, Allergan, Inc., Irvine. Investigative Opthamology & Visual Sciences. iovs.09-3474 (2009).
  23. Bead-based Multiplexed Immunoassays to Identify New Biomarkers in Maternal Serum to Improve First Trimester Down Syndrome Screening. 2009. M. P. H. Koster1,2* , J. L. A. Pennings3, S. Imholz3, W. Rodenburg3, G. H. A. Visser2, A. de Vries3 and P. C. J. I. Schielen1. 1Laboratory for Infectious Diseases and Screening, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands; 2Department of Obstetrics, Wilhelmina Children’s Hospital, University Medical Centre Utrecht (UMCU), Utrecht, The Netherlands; 3Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands. Prenatal Diagnosis. 29, 857-862.
  24. Genome-Wide mRNA Expression Analysis of Hepatic Adaptation to High-Fat Diets Reveals Switch from an Inflammatory to Steatotic Transcriptional Program. 2009. Marijana Radonjic1,2, Jorn R. de Haan1,2, Marjan J. van Erk1,2, Ko Willems van Dijk1,3, Sjoerd A. A. van den Berg1,3, Philip J. de Groot1,4, Michael Muller1,4, Ben van Ommen1,2. 1 Nutrigenomics Consortium, Top Institute Food and Nutrition, Wageningen, The Netherlands, 2 TNO Quality of Life, BU Biosciences, Zeist, The Netherlands, 3 Departments of General Internal Medicine and Human Genetics, Leiden University Medical Center, Leiden, The Netherlands, 4 Department of Human Nutrition, Wageningen UR, Wageningen, The Netherlands. Plos ONE. 4(8): e6646-e6646.
  25. RIP4 Regulates Epidermal Differentiation and Cutaneous Inflammation. 2009. Ryan B. Rountree1,4, Cynthia R. Willis2, Huyen Dinh2, Hal Blumberg2,5, Keith Bailey3, Charles Dean, Jr3, Jacques J. Peschon2,6 and Pamela M. Holland1. 1Department of Oncology, Amgen, Seattle, WA; 2Department of Inflammation, Amgen, Seattle, WA and 3Department of Pathology, Amgen, Seattle, WA, 4BN-ImmunoTherapeutics, Mountain View, CA; 5Novo Nordisk Inflammation Research Center, WA; 6Institute for Systems Biology, Seattle, WA. Journal of Investigative Dermatology. 23 July 2009, Online.
  26. Muscular Dystrophy Therapy by Nonautologous Mesenchymal Stem Cells: Muscle Regeneration Without Immunosuppression and Inflammation. 2009. Shabbir, D. Zisa, M. Leiker, C. Johnston, H. Lin, T. Lee. Department of Biochemistry, University at Buffalo, Buffalo, NY. Transplantation. 87, 1275-1282.
  27. Heart Failure Therapy Mediated by the Trophic Activities of Bone Marrow Mesenchymal Stem Cells: A Non-invasive Therapeutic Regimen. 2009. Shabbir, D. Zisa, G. Suzuki, T. Lee. Department of Biochemistry and Center for Research in Cardiovascular Medicine University at Buffalo, Buffalo, NY. American Journal Of Physiology; Heart And Circulatory Physiology. 296, H1888-1897.
  28. Vaccination with an Attenuated Strain of Francisella novicida Prevents T-Cell Depletion and Protects Mice Infected with the Wild-Type Strain from Severe Sepsis. 2009. J. Sharma, Q. Li, B. B. Mishra, M. J. Georges, J. M. Teale. South Texas Center for Emerging Diseases and Department of Biology, University of Texas at San Antonio, San Antonio, Texas. Infection and Immunity. 77, 4314-4326.
  29. Lethal Pulmonary Infection with Francisella Novicida is Associated with Severe Sepsis. 2009. J. Sharma, Q. Li, B. B. Mishra, C. Pena, J. M. Teale. South Texas Center for Emerging Diseases and Department of Biology, University of Texas at San Antonio, San Antonio, Texas. Journal of Leukocyte Biology. 86, 491-504.
  30. Metabolic and Neuroendocrine Responses to RXFP3 Modulation in the Central Nervous System. 2009. Steven W. Sutton,a Jonathan Shelton,a Craig Smith,b John Williams,b Sujin Yun,a Timothy Motley,a Chester Kuei,a Pascal Bonaventure,a Andrew Gundlach,b Changlu Liu,a and Timothy Lovenberga. aJohnson & Johnson Pharmaceutical Research & Development, LLC, San Diego,CA; bHoward Florey Institute, The University of Melbourne, Victoria, Australia. Annals of the New York Academy of Sciences. 1160, 242-249.
  31. Regression of Human Pancreatic Tumor Xenografts in Mice After a Single Systemic Injection of Recombinant Vaccinia Virus GLV-1h68. 2009. Y. A. Yu1, C. Galanis2, Y. Woo2, N. Chen1, Q. Zhang1, Y. Fong2, A. A. Szalay1,3. 1Genelux Corp, San Diego Science Center, San Diego, CA; 2Dept of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY; 3Rudolph-Virchow Center for Experimental Biomedicine, Institute of Molecular Infection Biology, Institute of Biochemistry, Biocenter, University of Wuerzburg, Wuerzburg, Germany. Molecular Cancer Therapeutics 8, 141-151.
  32. Atorvastatin Restores Endothelial Function in Offspring of Protein-Restricted Rats in a Cholesterol-Independent Manner. 2009. C. Torrens, C. J. Kelsall, L. A. Hopkins, F. W. Anthony, N. P. Curzen, M. A. Hanson. Institute of Developmental Sciences, School of Medicine, and Wessex Cardio-thoracic Unit, University of Southampton, Southampton, United Kingdom. Hypertension 53, 661-667.
  33. The Involvement of Pro-Inflammatory Cytokines in Nephrogenic Systemic Fibrosis – A Mechanistic Hypothesis Based on Preclinical Results From a Rat Model Treated with Gadodiamide 2009. T. Steger-Hartmann, et al. Bayer Schering Pharma, AG, Berlin, Germany. Experimental and Toxicologic Pathology Online.
  34. Multiplex Immunoassay Analysis of Biomarkers in Clinically Accessible Quantities of Human Aqueous Humor. 2009. R. K. Sharma1, A. Rogojina2, K.V. Chalam1, 1Department of Ophthalmology, University of Florida, Jacksonville, Fl; 2St. Jude Children’s Research Hospital, Memphis, TN. Molecular Vision 15, 60-69.
  35. Myocardial Oxidative Stress, Osteogenic Phenotype, and Energy Metabolism are Differentially Involved in the Initiation and Early Progression of δ-sarcoglycan-null Cardiomyopathy. 2009. C. Missihoun, D. Zisa, A. Shabbir, H. Lin, T. Lee. Department of Biochemistry and Center for Research in Cardiovascular Medicine, University at Buffalo, Buffalo, NY. Molecular and Cellular Biochemistry 321, 45-52.
  36. The Liver Toxicity Biomarker Study: Phase I Design and Preliminary Results. 2009. R. N. McBurney1, W. M. Hines1, L. S. Von Tungeln2, et al. 1BG Medicine, Inc., Waltham, MA; 2 National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR. Toxicol Pathol 37, 52-64.
  37. The Link Between Heightened Thrombogenicity and Inflammation: Pre-Procedure Characterization of the Patient at High Risk for Recurrent Events After Stenting. 2009. P. A. Gurbel, K. P. Bliden, R. P. Kreutz, J. Dichiara, M. J. Antonino, U. S. Tantry. Sinai Center for Thrombosis Research, Sinai Hospital of Baltimore, Baltimore, MD. Platelets 20, 97 - 104.
  38. Molecular Response to Cetuximab and Efficacy of Preoperative Cetuximab-Based Chemoradiation in Rectal Cancer. 2009. Debucquoy, K. Haustermans, A. Daemen, S. Aydin, L. Libbrecht, O. Gevaert, B. De Moor, S. Tejpar, W. H. McBride, F. Penninckx, P. Scalliet, C. Stroh, S. Vlassak, C. Sempoux, J.-P. Machiels, J Clin Oncol 27, 2751-2757.
  39. CCR5 Expression Levels Influence NFAT Translocation, IL-2 Production, and Subsequent Signaling Events during T Lymphocyte Activation. 2009. F. Camargo1, M. P. Quinones1,2, S. Mummidi1, S. Srinivas1, A. A. Gaitan1, K. Begum1, F. Jimenez1, S. VanCompernolle3, D. Unutmaz4, S. S. Ahuja1, S. K. Ahuja1,5. 1Veterans Administration Research Center for AIDS and HIV-1 Infection, San Antonio, TX and Department of Medicine, University of Texas Health Science Center, San Antonio, TX; 2Department of Psychiatry and Center for Bipolar Illness Intervention in Hispanic Communities, The University of Texas Health Science Center, San Antonio, TX; 3Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN; 4Department of Microbiology and Department of Pathology, NYU School of Medicine, NY, NY; 5Departments of Microbiology and Immunology and Department of Biochemistry, University of Texas Health Science Center, San Antonio, TX. J Immunol 182, 171-182.
  40. Development and Preliminary Evaluation of a Multivariate Index Assay for Ovarian Cancer. 2009. S. D. Amonkar, G. P. Bertenshaw, T. H. Chen, K. J. Bergstrom, J. Zhao, P. Seshaiah, P. Yip, B. C. Mansfield. Correlogic Systems, Inc., Rockville, MD. Plos ONE 4, e4599-e4599.

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2008

  1. "Host Tissue Damage" Signal ATP Impairs IL-12 and IFNγ Secretion in LPS Stimulated Whole Human Blood. 2008. Marek Nalos1, Stephen Huang1, Ronald Sluyter2, Alamgir Khan3, Brigitte Santner-Nanan4, Ralph Nanan1, Anthony S. McLean1. 1Department of Intensive Care, Nepean Hospital, University of Sydney, Penrith, Australia; 2Department of Medicine, Nepean Clinical School, University of Sydney, Penrith, Australia; 3Australian Proteome Analysis Facility, Macquarie University, Sydney, Australia; 4Department of Paediatrics, Nepean Clinical School, University of Sydney, Penrith, Australia. Intensive Care Medicine. 34:1981-1897, Online.
  2. TGF-β Signalling-Related Markers in Cancer Patients with Bone Metastasis. 2008. J. Baselga1, M. L. Rothenberg2, J. Tabernero1, J. Seoane1, T. Daly3, A. Cleverly3, B. Berry3, S. K. Rhoades3, C. A. Ray3, J. Fill3, D. L. Farrington3, L. Anne Wallace4, J. M. Yingling3, M. Lahn3, C. Arteaga2, M. Carducci4. 1Vall d’Hebron University Hospital, Barcelona, Spain; 2Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN; 3Eli Lilly & Co Research Labs, Indianapolis, IN; 4The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD. Biomarkers 13, 217-236.
  3. Rapid Microglial Response Around Amyloid Pathology after Systemic Anti-Aβ Antibody Administration in PDAPP Mice. 2008. J. Koenigsknecht-Talboo1,2, M. Meyer-Luehmann3, M. Parsadanian1,2, M. Garcia-Alloza3, M. B. Finn1,2, B. T. Hyman3, B. J. Bacskai3, D. M. Holtzman1,2. 1Department of Neurology and 2Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO; 3Department of Neurology, Massachusetts General Hospital, Charlestown, MA. J. Neurosci. 28, 14156-14164.
  4. Mechanisms of Oncostatin M-induced Pulmonary Inflammation and Fibrosis. 2008. A. Mozaffarian1, A. W. Brewer2, E. S. Trueblood2, I. G. Luzina3, N. W. Todd3, S. P. Atamas3, H. A. Arnett1. 1Department of Inflammation and 2Department of Pathology, Amgen, Inc, Seattle, WA; 3University of Maryland School of Medicine and Baltimore Veterans Affairs Medical Center, Baltimore, MD. Journal Of Immunology 181, 7243-7253.
  5. Multianalyte Profiling of Serum Antigens and Autoimmune and Infectious Disease Molecules to Identify Biomarkers Dysregulated in Epithelial Ovarian Cancer. 2008. Greg P. Bertenshaw1, Ping Yip1, Partha Seshaiah1, Jinghua Zhao1, Tzong-Hao Chen1, Wesley S. Wiggins1, James P. Mapes2 and Brian C. Mansfield1. 1Correlogic Systems, Inc., Rockville, Maryland and 2Rules-Based Medicine, Inc., Austin, Texas. Cancer Epidemiology, Biomarkers & Prevention. 17(10): p. 2872-2881.
  6. Ionizing Radiation-Induced Gene Modulations, Cytokine Content Changes and Telomere Shortening in Mouse Fetuses Exhibiting Forelimb Defects. 2008. Hanane Derradjia, Sofie Bekaertb, Tim De Meyerb, Paul Jacqueta, Khalil Abou-El-Ardatab, Myriam Ghardia, Michaux Arlettea and Sarah Baatouta. aLaboratory for Molecular and Cellular Biology Belgian Nuclear Research Centre, SCK·CEN, Boeretang 200, B-2400 Mol, Belgium; bDepartment for Molecular Biotechnology, FBW – Ghent University, Belgium. Developmental Biology. 322(2): p. 302-313.
  7. Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity. 2008. Shadmehr Demehri1&2, Zhenyi Liu1, Jonghyeob Lee1, Meei-Hua Lin3, Seth Crosby4, Christopher Roberts5, Perry Grigsby6, Jeffrey Miner3, Andrew Farr7 and Raphael Kopan1&2. 1Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, 2Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri, 3Renal Division, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, 4Genome Sequencing Center, Washington University School of Medicine, St. Louis, Missouri, 5Rosetta Inpharmatics, Seattle, Washington, 6Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri, 7Department of Biological Structure and Department of Immunology, University of Washington, Seattle, Washington. PLoS Biology. 6(5): p. e123.
  8. Mitogen-Activated Protein Kinase Kinase Signaling Promotes Growth and Vascularization of Fibrosarcoma. 2008. Yan Ding1, Elissa A. Boguslawski1, Bree D. Berghuis2, John J. Young1, Zhongfa Zhang3, Kim Hardy4, Kyle Furge5, Eric Kort3, Arthur E. Frankel6, Rick V. Hay4, James H. Resau2 and Nicholas S. Duesbery1. 1 Laboratories of 1Cancer and Developmental Cell Biology, 2Analytical, Cellular and Molecular Microscopy, 3Cancer Genetics, 4Noninvasive Imaging and Radiation Biology, and 5Computational Biology, Van Andel Research Institute, Grand Rapids, Michigan and 6Cancer Research Institute of Scott & White Memorial Hospital, Temple, Texas. Molecular Cancer Therapies: p. 1535-7163.MCT-07-2229.
  9. Combined Analysis of Monocyte and Lymphocyte Messenger RNA Expression with Serum Protein Profiles in Patients with Scleroderma. 2008. Hangjun Duan1, Jo Fleming1, David K. Pritchard1, Lynn M. Amon1, Jun Xue1, Heather A. Arnett2, Guang Chen2, Patricia Breen2, Jane H. Buckner3, Jerry A. Molitor3, Keith B. Elkon1 and Stephen M. Schwartz1. 1University of Washington, Seattle; 2Amgen, Inc., Seattle, Washington; 3Virginia Mason Research Center, Seattle, Washington. Arthritis & Rheumatism. 58(5): p. 1465-1474.
  10. A Mouse to Human Search for Plasma Proteome Changes Associated with Pancreatic Tumor Development. 2008. Vitor Faca1, Kenneth Song1, Hong Wang1, Qing Zhang1, Alexei Krasnoselsky1, Lisa Newcomb1, Ruben Plentz2, Sushma Gurumurthy2, Mark Redston3, Sharon Pitteri1, Sandra Pereira-Faca1, Renee Ireton1, Hiroyuki Katayama1, Veronica Glukhova1, Douglas Phanstiel1, Dean Brenner4, Michelle Anderson4, David Misek4, Nathalie Scholler1, Nicole Urban1, Matt Barnett1, Cim Edelstein1, Gary Goodman1, Mark Thornquist1, Martin McIntosh1, Ronald DePinho5&6, Nabeel Bardeesy2 and Samir1 Hanash. 1Fred Hutchinson Cancer Research Center, Seattle, Washington; 2Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; 3Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; 4University of Michigan, Comprehensive Cancer Center, Ann Arbor, Michigan; 5Center for Applied Cancer Science of the Belfer Institute for Innovative Cancer Science, Harvard Medical School, Boston, Massachusetts; 6Departments of Medical Oncology, Medicine and Genetics, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts. PLoS Medicine. 5(6): p. e123.
  11. IL-33 Amplifies Both Th1- and Th2-Type Responses through Its Activity on Human Basophils, Allergen-Reactive Th2 Cells, iNKT and NK Cells. 2008. Molly D. Smithgall, Michael R. Comeau, Bo-Rin Park Yoon, Dawn Kaufman, Richard Armitage and Dirk E. Smith. Department of Inflammation Research, Amgen Inc., Seattle, WA. International Immunology. 20(8): p. 1019-1030.
  12. MCP-I-Deficient Mice Show Reduced Neuroinflammatory Responses and Increased Peripheral Inflammatory Responses to Peripheral Endotoxin Insult. 2008. Wendy Thompson1&3, William Karpus2&3 and Linda Van Eldik1&3. 1Department of Cell and Molecular Biology, Northwestern University, Chicago, IL 60611; 2Department of Pathology, Northwestern University, Chicago, IL 60611 and 3Center for Drug Discovery and Chemical Biology, Northwestern University, Chicago, IL 60611. Journal of Neuroinflammation. 5(1): p. 35.
  13. Serum Biomarkers in a Mouse Model of Bacterial-Induced Inflammatory Bowel Disease. 2008. Anne E. Torrence1, Thea Brabb2, Joanne L. Viney3, Helle Bielefeldt-Ohmann4, Piper Treuting2, Audrey Seamons2, Rolf Drivdahl2, Weiping Zeng5 and Lillian Maggio-Price2. 1Washington National Primate Research Center, University of Washington, Seattle, WA; 2Department of Comparative Medicine, University of Washington, Seattle, WA; 3Department of Immunobiology, Amgen Corporation, Seattle, WA; 4Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Co; 5Department of Bioengineering, University of Washington, Seattle, WA. Inflammatory Bowel Diseases. 14(4): p. 480-490.
  14. FGF21 Corrects Obesity in Mice. 2008. Tamer Coskun, Holly A. Bina, Michael A. Schneider, James D. Dunbar, Charlie C. Hu, Yanyun Chen, David E. Moller and Alexei Kharitonenkov. Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285. Endocrinology: online en.2008-0816.
  15. Biomarker Sample Collection and Handling in the Clinical Setting to Support Early-Phase Drug Development. 2008. Chris B. Russell3, Sid Suggs4, Kristina M. Robson4, Keith Kerkof3, Lisa D. Kivman4, Kimberly H. Notari4, William A. Rees3, Natalia Leshinsky3 and Scott D. Patterson4. 3Department of Molecular Sciences, Amgen Inc, Seattle, Washington; 4Department of Molecular Sciences, Amgen Inc, Thousand Oaks, California. Methods in Pharmacology and Toxicology; Biomarker Methods in Drug Discovery and Development. DOI: 10.1007/978-1-59745-463-6_1: p. 1-26.
  16. Treatment of Sepsis-Induced Acquired Protein C Deficiency Reverses Angiotensin-Converting Enzyme-2 Inhibition and Decreases Pulmonary Inflammatory Response. 2008. Mark A. Richardson1, Akanksha Gupta1, Lee A. O'Brien2, David T. Berg1, Bruce Gerlitz1, Samreen Syed3, Ganesh R. Sharma1, Martin S. Cramer1, Josef G. Heuer1, Elizabeth J. Galbreath3 and Brian W. Grinnell1. 1Divisions of Biotechnology Discovery Research, 2Diagnostic/Experimental Medicine, 3Pathology, Lilly Research Labs, Lilly Corporate Center, Indianapolis, IN. Journal of Pharmacology And Experimental Therapeutics. 325(1): p. 17-26.
  17. Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-Induced Lung Fibrosis. 2008. Khalid Puthawala1, Nicos Hadjiangelis1, Steven C. Jacoby1, Emmanuel Bayongan1, Zhicheng Zhao2, Zhiwei Yang2, Mary Louise Devitt3, Gerald S. Horan4, Paul H. Weinreb4, Matvey E. Lukashev4, Shelia M. Violette4, Kristen S. Grant2, Cristina Colarossi2, Silvia C. Formenti3 and John S.Munger1,2. Departments of 1Medicine, 2Cell Biology and 3Radiation Oncology, New York University School of Medicine, New York, NY; and 4Biogen Idec, Cambridge, MA. American Journal of Respiratory and Critical Care Medicine. 177(1): p. 82-90.
  18. Identification of Transforming Growth Factor β1-Driven Genetic Programs of Acute Lung Fibrosis. 2008. Anne-Marie Pulichino1, I. Ming Wang3, Alexandre Caron1, James Mortimer1, Anick Auger1, Yves Boie1, Jack A. Elias4, Aileen Kartono1, Lijing Xu1, Joseph Menetski2 and Camil E. Sayegh1. 1Merck Frosst Centre for Therapeutic Research, Kirkland, Quebec, Canada, 2Merck Research Labs, Rahway, NJ, USA, 3Rosetta Inpharmatics LLC, a wholly owned subsidiary of Merck & Co., 4Section of Pulmonary and Critical Care Medicine, Yale, University School of Medicine, New Haven, CT. American Journal of Respiratory Cell and Molecular Biology. Published ahead of print on April 10, 2008. DOI: 10.1165/rcmb.2007-01860C: p. 2007-0186OC.
  19. Enzastaurin, an Oral Serine/Threonine Kinase Inhibitor, as Second- or Third-Line Therapy of Non-Small-Cell Lung Cancer. 2008. Yun Oh, Roy S. Herbst, Howard Burris, Ann Cleverly, Luna Musib, Michael Lahn and Gerold Bepler. M.D. Anderson Cancer Center, Houston, TX; The Sarah Cannon Cancer Center, Nashville, TN; Eli Lilly and Company, Indianapolis, IN; H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; and Eli Lilly and Company, Erlwood, United Kingdm. Journal of Clinical Oncology. 26(7): p. 1135-1141.
  20. Dexamethasone Inhibits High Glucose-, Tnf-α-, and IL-1β-Induced Secretion of Inflammatory and Angiogenic Mediators from Retinal Microvascular Pericytes. 2008. Alissar Nehme and Jeffrey Edelman. Department of Biological Sciences, Allergan Inc., Irvine, California. Investigative Ophthalmology and Visual Science. 49(5): p. 2030-2038.
  21. Initial Delay in the Immune Response to "Francisella tularensis" is Followed by Hypercytokinemia Characteristic of Severe Sepsis and Correlating with Upregulation and Release of Damage Associated Molecular Patterns. 2008. Chris A. Mares1, Sandra S. Ojeda1, Elizabeth G. Morris2, Qun Li2 and Judy M. Teale1, 2. 1Department of Microbiology and Immunology, The University of Texas Health Science Center, San Antonio, Texas; 2South Texas Center for Emerging Infectious Diseases and Department of Biology, The University of Texas, San Antonio, Texas., Infection and Immunity. 76(7): p. 3001-3010.
  22. Circulating Markers Reflect Both Anti- and Pro-Atherogenic Drug Effects in ApoE-Deficient Mice. 2008. Birong Liao1, Eileen McCall2, Karen Cox1, Chung-Wein Lee1, Shuguang Huang5, Richard E. Higgs3, Li-Chun Chio1, Eugene Zhen1, John E. Hale1, Nancy K. Jackson2, Pamela G. Rutherford2, Xiao-de Huang2, Donetta Gifford-Moore2, Kwan Hui2, Kevin Duffin1, Kenneth E. Gould2 and Mark Rekhter2. 1Integrative Biology, 2Atherosclerosis and Metabolic Syndrome Drug Hunting Team, 3Discovery Statistics, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN. Biomarker Insights. 3: p. 147-157.
  23. Two Distinct Activation States of Plasmacytoid Dendritic Cells Induced by Influenza Virus and CpG 1826 Oligonucleotide. 2008. Amaya Iparraguirre1, John W. Tobias2, Scott E. Hensley1, Katherine S. Masek3, Lois L. Cavanagh1, Michael Rendl6, Christopher A. Hunter3, Hildegund C. Ertl1, Ulrich H. von Andrian7 and Wolfgang Weninger1, 4,5. 1Immunology Program, The Wistar Institute; 2Penn Bioinformatics Core; 3School of Veterinary Medicine; 4Dermatology; 5Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA; 6Rockefeller University, New York, NY; 7Department of Pathology, Harvard Medical School, Boston, MA. Journal of Leukocyte Biology. 83(3): p. 610-620.
  24. Biomarker Analysis by Fluorokine Multianalyte Profiling Distinguishes Patients Requiring Intervention from Patients with Long-Term Quiescent Coronary Artery Disease: A Potential Approach to Identify Atherosclerotic Disease Progression. 2008. Paul Gurbel, Rolf Kreutz, Kevin Bliden, Joseph DiChiara and Udaya Tantry. Sinai Center for Thrombosis Research, Baltimore, MD. American Heart Journal. 155(1): p. 56-61.
  25. Tissue Distribution and Toxicity of Intravenously Administered Titanium Dioxide Nanoparticles in Rats. 2008. Eric Fabian1, Robert Landsiedel1, Lan Ma-Hock1, Karin Wiench1, Wendel Wohlleben2 and Ben Van Ravenzwaay1. 1BASF Product Safety, BASF Aktiengesellschaft, Ludwigshafen, Germany; 2BASF Polymer Physics, BASF Aktiengesellschaft, Ludwigshafen, Germany. Archives of Toxicology. 82(3): p. 151-157.
  26. Biomarker Profiles in Serum and Saliva of Experimental Sjogren's Syndrome: Associations with Specific Autoimmune Manifestations. 2008. Nicolas Delaleu1, Heike Immervoll2, 3, Janet Cornelius4 and Roland Jonsson1, 5,. 1Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Haukelandsveien, Bergen, Norway; 2Section of Pathology, The Gade Institute, University of Bergen, Jonas Liesvei, Bergen, Norway; 3Department of Pathology, Haukeland University Hospital, Jonas Liesvei, Bergen, Norway; 4Department of Pathology, Immunology and Laboratory Medicine, University of Florida, SW Archer Road, Gainesville, FL, USA; 5Department of Rheumatology, Haukeland University Hospital, Bergen, Jonas Liesvei, Bergen, Norway; 6Department of Otolaryngology, Head and Neck Surgery, Haukeland University Hospital, Bergen, Jonas Liesvei, Bergen, Norway. Arthritis Research and Therapy. 10(1): p. R22.
  27. Antiinflammatory and Antiatherogenic Effects of the NF-Κb Inhibitor Acetyl-11-Keto-β-Boswellic Acid in LPS-Challenged ApoE -/- Mice. 2008. Clarisse Cuaz-Perolin1,2,3, Ludivine Billiet1,2,3, Eric Bauge1,2,3, Corinne Copin1,2,3, Daniel Scott-Algara4, Felicitas Genze5, Berhold Buchele5, Tatiana Syrovets5, Thomas Simmet5 and Mustapha Rouis1,2. 1Inserm, Lille, France; 2Departement d’Atherosclerose, Institut Pasteur de Lille, Lille, France; ,3 Universite de Lille, Faculte de Pharmacie, Lille, France; 4Unite de Regulation des Infections Retrovirales; Institute Pasteur, Paris, France; 5Ulm University, Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm, Germany. Arteriosclerosis, Thrombosis, and Vascular Biology. 28(2): p. 272-277.
  28. Endothelial Activation Markers in Anemic Non-Dialysis Chronic Kidney Disease Patients. 2008. T. V. Patel, B. V. Mittal, S. R. Keithi-Reddy, J. S. Duffield, A. K. Singh. Renal Division, Brigham and Women’s Hospital, and Harvard Medical School, Boston, MA. Nephron Clinical Practice 110, c244-c250.

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2007

  1. The Protective Effect of the Blood Brain Barrier from Systemic Cytokines in an Animal Femur Fracture Model. 2007. M. Ott, A. T. Davis, W. Vanderkolk, J. H. Resau, D. H. Deheer, C. B. Jones, C. Stouffer, E. W. Kubek. Grand Rapids/Michigan State University General Surgery Residency, Grand Rapids, MI. The Journal Of Trauma 63, 591-595.
  2. Sirtuin Regulates Cigarette Smoke-Induced Proinflammatory Mediator Release Via RelA/p65 NF-ΚB in Macrophages in Vitro and in Rat Lungs in Vivo: Implications for Chronic Inflammation and Aging. 2007. Se-Ran Yang, Jessica Wright, Mark Bauter, Kathryn Seweryniak, Aruna Kode and Irfan Rahman. Environmental Medicine, University of Rochester, Rochester, New York, United States. American Journal of Physiology - Lung Cellular and Molecular Physiology. 292(2): p. L567-L576.
  3. Lysosomal Dysfunction Results in Altered Energy Balance. 2007. Josh C Woloszynek1, 2, Trey Coleman1, 3, Clay F Semenkovich1, 3 and Mark S. Sands1, 2. 1Departments of Medicine, 1Genetics, and 3Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO. Journal of Biological Chemistry. 282(49): p. 35765-35771.
  4. Interleukins 27 and 6 Induce Stat3-Mediated T Cell Production of Interleukin 10. 2007. Jason S. Stumhofer1, Jonathan S. Silver1, Arian Laurence2, Paige M. Porrett3, Tajie H. Harris1, Laurence A. Turka3, Matthias Ernst4, Christiaan J. M. Saris5, John J. O'Shea2 and Christopher A. Hunter1. 1Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 2Molecular Immunology and Inflammation Branch, National Institute of Arthritis and Muskoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 3Department of Medicine, University of Pennsylvania, Philadelphia, PA, 4Ludwig Institute for Cancer Research, Parkville, Victoria 3050, Australia, 5Department of Inflammation Research, Amgen, Thousand Oaks, California. Nature Immunology. 8(12): p. 1363-1371.
  5. Signal Transducer and Activator of Transcription 3 Signaling within Hepatocytes Attenuates Systemic Inflammatory Response and Lethality in Septic Mice. 2007. Ryotaro Sakamori1, Tetsuo Takehara1, Chihiro Ohnishi1, Tomohide Tatsumi1, Kazuyoshi Ohkawa1, Kiyoshi Takeda2, Shizuo Akira3 and Norio Hayashi1. 1Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan, 2Department of Molecular Genetics, Medical Institute of Bioregulation, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan, 3Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan. Hepatology. 46(5): p. 1564-1573.
  6. Pulmonary Delivery of Adenovirus Vector Formulated with Dexamethasone-Spermine Facilitates Homologous Vector Re-Administration. 2007. A. R Price1, 4, M. P. Limberis2, 4, J. M. Wilson2 and S. L Diamond1, 3. 1Department of Bioengineering, Institute for Medicine and Engineering, Vagelos Research Laboratory, University of Pennsylvania, PA, 2Department of Pathology and Laboratory Medicine, University of Pennsylvania, PA, and 3Department of Chemical and Biomolecular Engineering, Institute for Medicine and Engineering, Vagelos Research Laboratory, University of Pennsylvania, PA. Gene Therapy. 14(22): p. 1594-1604.
  7. Phase I Study of Eptifibatide in Patients with Sickle Cell Anaemia. 2007. Sheritha P. Lee1, Kenneth I. Ataga2, Mohamed Zayed1, Jeanne M. Manganello3, Eugene P. Orringer2, David R. Phillips3 and Leslie V Parise1, 4. Departments of 1Pharmacology, 2Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 3Millennium Pharmaceuticals, South San Francisco, CA and, 4Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. British Journal of Haematology. 139(4): p. 612-620.
  8. The Metabolic State of Diabetic Monkeys Is Regulated by Fibroblast Growth Factor-21. 2007. Alexei Kharitonenkov1, Victor J. Wroblewski1, Anja Koester1, Yun-Fei Chen1, Cathleen K. Clutinger1, Xenia T. Tigno2, Barbara C. Hansen2, Armen B. Shanafelt1 and Garret J. Etgen1. 1Lilly Research Laboratories, A Division of Eli Lilly and Co., Indianapolis, IN; 2The Obesity, Diabetes and Aging Research Center, Departments of Internal Medicine and Pediatrics, College of Medicine, University of South Florida, Tampa, FL Endocrinology. 148(2): p. 774-781.
  9. Modeled Gravitational Unloading Induced Downregulation of Endothelin-1 in Human Endothelial Cells. 2007. Manfred Infanger1, Claudia Ulbrich2, Sarah Baatout3, Markus Wehland2, Reinhold Kreutz2, Johann Bauer4, Jirka Grosse2, Sonia Vadrucci5, Augusto Cogoli5, Hanane Derradji3, Mieke Neefs3, Sabine Küsters6, Mike Spain6, Martin Paul2 and Daniela Grimm2. 1Department of Trauma and Reconstructive Surgery and 2Institute of Clinical Pharmacology and Toxicology, Charité-University Medical School, Campus Benjamin Franklin, Center of Space Medicine, Berlin, Germany, 3Laboratory of Radiobiology and Microbiology, Belgian Nuclear Research Centre, Mol, Belgium, 4Max-Planck Institute of Biochemistry, Martinsried, Germany, 5Zero-g Lifetec GmbH and Space Biology Group, ETH Zurich, Switzerland, 6Rules Based Medicine, Austin, TX, USA. Journal of Cellular Biochemistry. 101(6): p. 1439-1455.
  10. Activated Protein C Ameliorates LPS-Induced Acute Kidney Injury and Downregulates Renal INOS and Angiotensin 2. 2007. Akanksha Gupta1, George J. Rhodes2, David T.1 Berg1, Bruce Gerlitz1, Bruce A. Molitoris2 and Brian W. Grinnell1. 1 Division of Biotechnology Discovery Research, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis and 2 Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN. American Journal Physiology - Renal Physiology. 293(1): p. F245-F254.
  11. Multi-Analyte Profiling of Post-Myocardial Infarction Plasma Samples. 2007. G. Patricia Escobar and Merry L. Lindsey. Medicine/Cardiology, The University of Texas Health Science Center at San Antonio, San Antonio, TX. FASEB J. 21(746).
  12. Neighboring Adipocytes Participate in the Bone Marrow Microenvironment of Multiple Myeloma Cells. 2007. J. Caers1, S. Deleu1, Z. Belaid2, H. De Raeve3, E. Van Valckenborgh1, E. De Bruyne1, M. P. DeFresne2, I. Van Riet1, B. Van Camp1 and K. Vanderkerken1. 1Laboratory of Hematology and Immunology, Vrije Universiteit Brussels, Brussels, Belgium, 2Laboratory of Histology and Cytology, Universite de Liege, Liege, Belgium, 3 Department of Pathology, Antwerp University, Antwerp, Belgium. Leukemia. 21(7): p. 1580-1584.
  13. Opposing Activities of Two Novel Members of the IL-1 Ligand Family Regulate Skin Inflammation. 2007. Hal Blumberg1, Huyen Dinh1, Esther S. Trueblood2, James Pretorius4, David Kugler1, Ning Weng3, Suzanne T. Kanaly2, Jennifer E. Towne1, Cynthia R. Willis1, Melanie K. Kuechle5, John E. Sims1 and Jacques J. Peschon1. 1Department of Inflammation, 2Department of Pathology, 3Department of Biostatistics, Amgen, Seattle, WA, 4Department of Pathology, Amgen, Thousand Oaks, CA, 5Department of Dermatology, University of Washington School of Medicine, Seattle, WA. Journal of Experimental Medicine. 204(11): p. 2603-2614.
  14. Femoral Artery Neointimal Hyperplasia is Reduced after Wire Injury in Ref-1+/- Mice. 2007. David L. Basi1, Neeta Adhikari2, Ami Mariash2, Qinglu Li2, Esther Kao2, Sureni V. Mullegama2 and Jennifer L. Hall2. 1Developmental/Surgical Science, 2Medicine/Cardiology, 3Developmental/Surgical Science, 4Medicine, University of Minnesota, Minneapolis, MN. American Journal - Heart and Circulatory Physiology. 292(1): p. H516-H521.

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2006

  1. Cutting Edge: Interleukin 17 Signals through a Heteromeric Receptor Complex. 2006. Dean Toy1, David Kugler1, Martin Wolfson2, Tim Vanden Bos2, Jesse Gurgel3, Jonathan Derry4, Joel Tocker1 and Jacques Peschon1. Departments of Inflammation1, Protein Sciences2, Oncology3, and Molecular Sciences4, Amgen, Seattle WA. Immunology. 177(1): p. 36-39.
  2. Using Genetically Engineered Mouse Models of Cancer to Aid Drug Development: An Industry Perspective. 2006. Mallika Singh and Leisa Johnson. Genentech, Inc., South San Francisco, CA. Clinical Cancer Research. 12(18): p. 5312-5328.
  3. Fumaric Acid Esters Are Effective in Chronic Experimental Autoimmune Encephalomyelitis and Suppress Macrophage Infiltration. 2006. S. Schilling1, S. Goelz2, R. Linker1, F. Luehder1 and R. Gold1. 1Institute for Multiple Sclerosis Research, University of Goettingen, Goettingen, Germany and 2BiogenIdec Cambridge, MA, USA. Clinical and Experimental Immunology. 145(1): p. 101-107.
  4. Strain Differences Influence Murine Pulmonary Responses To "Stachybotrys Chartarum". 2006. Jamie H. Rosenblum Lichtenstein, Ramon M. Molina, Thomas C. Donaghey and Joseph D. Brain. Department of Environmental Health, Harvard School of Public Health, Boston, MA. American Journal of Respiratory Cell and Molecular Biology. 35(4): p. 415-423.
  5. Effects of the Incubation In Vitro with Sorbents on Serum Proteomic Pattern and Cytokine Concetration in Cancer Patients During Chemotherapy - Preliminary Results. 2006. Francesco Piccolominia, Mary Lou Wrattenb, Luisa Serenia, Ettore Balestreria, Elena Donadioc, Antonio Feliciolic, Roman Feliciolia and Carlo Donadiod. aIstituto di Biofisica, CNR, Pisa, Italy; bBellco Scientific Affairs, Mirandola, Italy; cDipartimento di Anatomia, Biochimica e Fisiologia Veterinaria, Universita di Pisa, Pisa, Italy; dDipartimento di Medicina Internal, Universita di Pisa, Pisa Italy. Biomedecine & Pharmacotherapy. 60(8): p. 463-467.
  6. TWEAK is a Novel Arthritogenic Mediator. 2006. Stuart J. Perper1, Beth Browning1, Linda C. Burkly1, Shawn Weng1, Cindy Gao1, Keith Giza1, Lihe Su1, Leticia Tarilonte1, Thomas Crowell1, Luis Rajman1, Laura Runkel1, Martin Scott1, Gerald J. Atkins2, David M. Findlay2, Timothy S. Zheng1 and Henry Hess1. 1Biogen Idec, Cambridge, MA, 2Dept. of Orthopedics and Trauma, University of Adelaide, Adelaide, Australia. Immunology. 177(4): p. 2610-2620.
  7. A Phase II Pilot Trial of Low Dose, Continuous Infusion, Or "Metronomic", Paclitaxel and Oral Celecoxib in Patients with Metastatic Melanoma. 2006. D. F. McDermott, D. C. Cho, J. R. Merchan, R. S. Bhatt, V. Seery, J. L. Mosher, M. B. Farquhar, J. W. Mier, M. B. Atkins and V. P. Sukhatme. Renal Division, Beth Israel Deaconess Medical Cntr., Boston, MA. Journal of Clinical Oncology, 2006 ASCO Annual Meeting Proceedings Part I. 24(18S).
  8. Effects of Cidofovir Treatment on Cytokine Induction in Murine Models of Cowpox and Vaccinia Virus Infection. 2006. Corinna W. Knorr1, Stanley D. Allen1, Anthony R. Torres2 and Donald F. Smee1. 1Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, 2Center for Persons with Disabilities, Utah State University, Logan, UT. Antiviral Research. 72(2): p. 125-133.
  9. Effects of Hyperglycemia and Insulin Therapy on Outcome in a Hyperglycemic Septic Model of Critical Illness. 2006. Josef Heuer, Ganesh Sharma, Tonghai Zhang, Chunjin Ding, Dianna Bailey, Eddie Stephens, Kimberly Holmes, Renee Grubbs, Kelly Fynboe, Yun-Fei Chen and Joseph Jakubowski. Eli Lilly and Company, Indianapolis, IN. Journal of Trauma-Injury Infection & Critical Care. 60(4).
  10. Murine Embryonic Stem Cells Secrete Cytokines/Growth Modulators that Enhance Cell Survival/Anti-Apoptosis and Stimulate Colony Formation of Murine Hematopoietic Progenitor Cells. 2006. Ying Guo, Barbara Graham-Evans and Hal E. Broxmeyer. Dept. of Microbiology/ Immunology, Indiana University School of Medicine, Indianapolis, IN. Stem Cells. 24(4): p. 850-856.
  11. Testing the Viability of Stored Frozen Serum Samples from the Air Force Health Study Using Human Multi-Analyte Profiles (MAPS). 2006. K. Fox1 and M. Pavuk2. 1USAF School of Aerospace Medicine, Brooks City-Base, San Antonio, TX, 2SpecPro Inc., 12500 San Pedro Ave., Suite 670, San Antonio, TX. Organohalogen Compounds. 68(206): p. 1390-1393
  12. Characterization of the Inflammatory Response to a Highly Selective PDE4 Inhibitor in the Rat and the Identification of Biomarkers that Correlate with Toxicity. 2006. Gregory N. Dietsch1, Chris R. DiPalma1, Russell J. Eyre1, Tuan Q. Pham1, Karen M. Poole1, Noah B. Pefaur2, William D. Welch1, Esther Trueblood1, William D. Kerns3 and Suzanne T. Kanaly1. 1 ICOS Corporation, Bothell, Washington, 2 ICOS Corporation, currently at Pacific Northwest National Laboratories, Richland, Washington, 3 Pharma Consulting, Harvard, Boston, MA. Toxicologic Pathology. 34(1): p. 39-51.

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2005

  1. Hypoxia-Induced Neutrophil Survival is Mediated by HIF-1α-Dependent NF-ΚB Activity. 2005. Sarah R. Walmsley1, Cristin Print2, Neda Farahi1, Carole Peyssonnaux3, Randall S. Johnson3, Thorsten Cramer3, Anastasia Sobolewski1, Alison M. Condliffe1, Andrew S. Cowburn1, Nicola Johnson2 and Edwin R. Chilvers1. 1Division of Respiratory Medicine, 2Dept. of Pathology, University of Cambridge, Cambridge, UK, 3Molecular Biology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA. Journal of Experimental Medicine. 201(1): p. 105-115.
  2. Prophylactic Administration of Abatacept Prevents Disease and Bone Destruction in a Rat Model of Collagen-Induced Arthritis. 2005. C. Kliwinski, D. Kukral, J. Postelnek, B. Krishnan, L. Killar, A. Lewin, S. Nadler and R. Townsend. Bristol-Myers Squibb, Princeton, NJ. Journal of Autoimmunity. 25(3): p. 165-171.
  3. Multiplex Proteomic Approaches to Sepsis Research: Case Studies Employing New Technologies. 2005. Josef Heuer, David Cummins and Brian Edmonds. Eli Lilly and Company, Indianapolis, IN. Expert Review of Proteomics. 2(5): p. 669-680.
  4. Adoptive Transfer of in Vitro-Stimulated CD4+CD25+ Regulatory T Cells Increases Bacterial Clearance and Improves Survival in Polymicrobial Sepsis. 2005. Josef G. Heuer1, Tonghai Zhang1, Jingyong Zhao2, Chunjin Ding1, Martin Cramer1, Kathy L. Justen2, Steven L. Vonderfecht1 and Songqing Na2. 1Biotechnology Discovery Research, 2Bone and Inflammation, Eli Lilly and Company, Indianapolis, IN. Immunology. 174(11): p. 7141-7146.
  5. Mkks-Null Mice Have a Phenotype Resembling Bardet-Biedl Syndrome. 2005. Melissa A Fath1, 5, Robert F. Mullins2, Charles Searby1, 5, Darryl Y Nishimura1, 5, Jun Wei1, 5, Kamal Rahmouni3, Roger E. Davis1, Marwan K. Tayeh1, Michael Andrews1, 5, Baoli Yang4, Curt D. Sigmund3, Edwin M. Stone2, 5, and Val C. Sheffield1, 5. 1Dept. of Pediatrics, Division of Medical Genetics, 2Dept. of Ophthalmology, 3Dept. of Internal Medicine, 4Dept. of Obstetrics and Gynecology and 5Howard Hughes Medical Institute, University of Iowa, Iowa City, IA. Human Molecular Genetics. 14(9): p. 1109-1118.

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2004

  1. Simultaneous Analysis of Host and Pathogen Interactions During an in Vivo Infection Reveals Local Induction of Host Acute Phase Response Proteins, a Novel Bacterial Stress Response, and Evidence of a Host-Imposed Metal Ion Limited Environment. 2004. S. Timothy Motley, Brian J. Morrow, Xuejun Liu, Ingrid L. Dodge, Antonella Vitiello, Christine K. Ward and Karen Joy Shaw. Johnson & Johnson Pharmaceutical Research and Development, La Jolla, CA. Cellular Microbiology. 6(9): p. 849-865.
  2. LXR-Dependent Gene Expression is Important for Macrophage Survival and the Innate Immune Response. 2004. Sean B. Joseph1, 4, Michelle N Bradley1, 4, Antonio Castrillo1, 4, Kevin W. Bruhn2, Puiying A. Mak3, Liming Pei1, John Hogenesch3, Ryan M. O'Connell2, Genhong Cheng2, Enrique Saez3, Jeffery F. Miller2 and Peter Tontonoz1. 1Dept. of Pathology and Laboratory Medicine, 2Dept. of Microbiology Immunology and Molecular Genetics, UCLA, Los Angeles, CA, 3Genomics Institute of the Novartis Research Foundation, San Diego, CA. Cell. 119(2): p. 299-309.
  3. Evaluation of Protein C and Other Biomarkers as Predictors of Mortality in a Rat Cecal Ligation and Puncture Model of Sepsis. 2004. Josef Heuer, Ganesh Sharma, Bruce Gerlitz, Tonghai Zhang, Dianna Bailey, Chunjin Ding, David Berg, Douglas Perkins, Eddie Stephens, Kimberly Holmes, Renee Grubbs, Kelly Fynboe, Yun-Fei Chen, Brian Grinnell and Joseph Jakubowski. Eli Lilly and Company Discovery Research Laboratory, Indianapolis, IN. Critical Care Medicine. 32(7): p. 1570-1578.
  4. Validation of a New Highly Standardised, Lab-Independent Whole-Blood Leukocyte Function Assay for Clinical Trials (ILCS®). 2004. M. Schmolzc, T.L. Hursta,*, D.M. Baileyb, J.R. Powella, R.J. Forseya, J.M. Thompsona, C. Williamsb, G. Pawelecd. aUnilever Research Colworth, Sharnbrook, MK 44 1LQ England, UK, bMuscle Research Group, Loughborough University, Leicestershire, UK, cExperimental and Diagnostic Immunology (EDI) GmbH, Markwiesenstr. 55, D-72770 Reutlingen, Germany, dTubingen Ageing and Tumour Immunology Group, ZMF, Section for transplantation immunology and immuno-haematology, Waldhornlestr. 22, D-72072 Tubingen, Germany. Experimental Gerontology 39: 667-671