Introducing a completely new capability in drug development.
TruCulture™ takes the complexity and error out of traditional ex vivo tests. Elaborate protocols and specialized labs are replaced with a standard blood draw into a TruCulture™ tube. By its simple design, TruCulture™ eliminates sample manipulation and preserves the body's immune signaling components. This precise method coupled with our proven biomarker (MAP) testing services provides highly reproducible data in one cost-effective assay.
“Things should be made as simple as possible, but not any simpler.”
— Albert Einstein
Ideal for multi-center trials, TruCulture™ is a simple, self-contained whole blood culture system that can be deployed in sites without specialized facilities or training. Using TruCulture™, collection and culture methods are standardized, providing dramatic cost savings and robust data. TruCulture™ is designed for cytokine analysis, but has demonstrated compatibility with gene expression analysis as well. See how your peers are using TruCulture.
“TruCulture allows us to collect data we simply couldn’t collect before.”
— Top 10 Pharma customer
TruCulture™ tubes are available with or without standard stimulants and can be manufactured to contain your investigational stimulant or compound.
Improved quality, throughput, and dramatically
reduced costs are as easy as One, Two, Three:
How it works
After a simple blood draw and a study-defined incubation period, your samples are ready for a variety of downstream applications. To achieve the best results, we recommend utilizing our TruCulture MAP testing services along with the tubes.
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Specifications
In addition to custom TruCulture tube preparations with a compound of interest, tubes can be ordered with these classical immune stimulants:
| Stimulant | Major Target Cells |
| Lipopolysaccharide (LPS) | Monocytes, T-cells |
| Zymosan | Granulocytes, Monocytes |
| Anti-CD3 antibody | Th1>Th2 |
| Anti-CD3 antibody + Anti-CD28 antibody | Th1, Th2, regulatory T cells |
| Staphylococcal Enterotoxin type B (SE-B) | Th1>>Th2 |
| LPS +SE-B | Monocytes, T-cells and Th1>>Th2 |
If you are interested in adding a custom compound or placing an order for TruCulture, please contact your sales representative, or e-mail info@rulesbasedmedicine.com or fill out the form below.