Press

Rules-Based Medicine, Inc. Awarded Funding from the Cancer Prevention and Research Institute of Texas

Multimillion Dollar Award to Expand OncologyMAP™ Program for Novel Cancer Tests

AUSTIN, TX (June 23, 2010) — Rules-Based Medicine, Inc. (RBM) today announced the Cancer Prevention and Research Institute of Texas (CPRIT) has granted it a Company Commercialization Award to expand and enhance the OncologyMAP™ program for discovery and development of novel diagnostic and prognostic cancer tests. The award of approximately $3 million will fund research and development to more than double the number of cancer-associated biomarker assays in RBM's new OncologyMAP™ product.

Rules-Based Medicine and Psynova Neurotech Announce Companion Diagnostic Collaboration with Roche

Utilizing Psynova's schizophrenia biomarker portfolio and RBM's DiscoveryMAP™ technology

AUSTIN, TX (December 2, 2009) — Rules-Based Medicine, Inc. (RBM) today announced that Psynova Neurotech Limited (Cambridge UK), a majority-owned subsidiary of RBM, has executed an exclusive research and licensing agreement with Roche to collaborate on the discovery, development, validation and commercialization of diagnostic immunoassays to aid the clinical development and commercial differentiation of novel treatments for schizophrenia.


Rules-Based Medicine Forms Biomarker Alliance with Covance Inc.

Deal Expands Access to Clinical Trials Market for Multiplexed Biomarker Services

SAN DIEGO, CA — November 18, 2009 — Rules-Based Medicine, Inc. (RBM) today announced it has entered into a biomarker alliance and services agreement with Covance Inc. (NYSE:CVD) that will provide biotechnology and pharmaceutical companies with a powerful combination of biomarker technologies and services for use in drug development. Under terms of the agreement, Covance will use RBM as its exclusive third-party provider of multiplexed protein biomarker testing services, and RBM shall use Covance as its exclusive referral source for laboratory testing services. Financial terms of the agreement were not disclosed.


Rules-Based Medicine, Inc. Names Don Beamish to Lead Sales & Marketing for Diagnostic Expansion

AUSTIN, Texas — November 11, 2009 — Rules-Based Medicine, Inc. (RBM), today announced that Don Beamish has joined the Company as vice president, commercial development. In this newly created position Beamish will leverage his neuroscience pharmaceutical marketing expertise in leading sales and marketing initiatives to support the intended launch of RBM's neuropsychiatric diagnostics services. RBM recently announced the identification of a biomarker panel demonstrating clinical utility for the differential diagnosis of schizophrenia.


Rules-Based Medicine Introduces CardiovascularMAP™ Multiplex Biomarker Panel To Aid CVD Development

Austin, Texas, October 28, 2009 — Rules-Based Medicine (RBM), a leading multiplexed biomarker testing laboratory, today announced the launch of CardiovascularMAP™, a research tool designed specifically to advance drug development aimed at the treatment of cardiovascular disease (CVD). Designed in collaboration with leading pharmaceutical and biotechnology research groups, the 50-biomarker panel combines biomarkers most commonly associated with CVD progression with additional markers to identify new patterns of disease, resulting in a potentially powerful new tool for researchers.


Rules-Based Medicine, Inc. and Psynova Neurotech Ltd. Identify Diagnostic Biomarker Panel for Schizophrenia

Austin, Texas and Cambridge, England, October 20, 2009 — Rules-Based Medicine, Inc. (RBM) and Psynova Neurotech Ltd. (Psynova) today announced the discovery and characterization of a combination of protein biomarkers demonstrating utility as an adjunctive aid in the differential diagnosis of schizophrenia. As a result of this clinical milestone, RBM has made additional investments in Psynova, and now has a controlling interest in the company.


Rules-Based Medicine, Inc. Launches DiscoveryMAP™ Service for Drug and Diagnostic Development

Austin, Texas, June 17, 2009 — Rules-Based Medicine, Incorporated (RBM), the world's leading multiplexed biomarker testing laboratory, today announced the availability of the most comprehensive collection of quantitative immunoassays for use in advancing safety, efficacy and efficiency in drug and diagnostic development. The new service, DiscoveryMAP™ v 1.0, offers customers dynamic coverage of most physiologically relevant pathways, providing biological information and leads for further study. This unique and comprehensive offering increases the odds of identifying new protein biomarker patterns in almost any drug development or diagnostic discovery project.


Rules-Based Medicine, Inc. Names Tony Barnes to Lead Expanded Diagnostics Business

Austin, Texas, June 2, 2009 — Rules-Based Medicine, Incorporated (RBM), the leading biomarker testing service, today announced that Tony Barnes, Ph.D., MBA, has joined the Company as vice president, clinical diagnostics. Barnes will provide strategic marketing and operational leadership as RBM commercializes new biomarker-based diagnostic tests.


Rules-Based Medicine, Inc. Launches Human Kidney Damage Biomarker Panel

Complements the RBM Rat Kidney Panel developed in conjunction with the Critical Path Initiative

AUSTIN (January 15, 2009) — Rules-Based Medicine, Inc. (RBM), the world's leading multiplexed biomarker testing laboratory, today announced the launch of its Human Kidney Multi-Analyte Profile (MAP), a cost-effective biomarker testing service designed to aid pharmaceutical and biotechnology companies in their efforts to improve drug development through better understanding of drug toxicity. The Human Kidney MAP will be used in clinical trials to reveal early signs and locations of drug-induced kidney damage, known as renal toxicity or nephrotoxicity, thereby guiding important decisions on lead compounds and dosage.


National Cancer Institute Awards Small Business Innovation Research Contract To Rules-Based Medicine, Inc.

RBM to Expand Research Collaboration with Correlogic Systems, Inc. Aimed at Multiplex Diagnostic Tests for Ovarian Cancer

AUSTIN, TX (December 18, 2008) — Rules-Based Medicine, Inc. (RBM) and Correlogic Systems, Inc. today announced the award of a National Cancer Institute (NCI) Small Business Innovation Research (SBIR) contract to RBM that will further research on ovarian cancer diagnostic tests. The contract was awarded through a peer-reviewed competitive process to develop biomarker panels for the early detection of cancer and includes a Phase I "Fast-Track" component and Phase II option, together totaling $1.15 million.


Race for mental illness test on

Rules-Based Medicine working on fast, accurate blood diagnosis tool.

By Lilly Rockwell
AMERICAN-STATESMAN STAFF

AUSTIN, TX (August 11, 2008) — Ever since the recent discovery that schizophrenia can be diagnosed using blood analyses instead of traditional psychiatric methods, companies have rushed to find a way to bring such a test to market.


Rules-Based Medicine Commercializes New Toxicity Biomarker Panel in Conjunction with FDA, EMEA, C-Path and PSTC

For use in pre-clinical trials to evaluate early renal toxicity, new Rat Kidney MAP will aid in faster development of safer drugs

AUSTIN, TX (June 30, 2008) — Rules-Based Medicine, Inc. (RBM), the leading multiplexed biomarker testing laboratory for the life sciences industry, announced today that it has commercialized a new biomarker panel to aid pharmaceutical and biotech companies evaluate renal toxicity in rats for pre-clinical drug trials. RBM’s Rat Kidney MAP (multi-analyte profile) measures key biomarkers found in urine that can provide additional information about drug-induced damage to kidney cells, known as renal toxicity or nephrotoxicity.


Rules-Based Medicine and Psynova Neurotech to Co-Develop Blood Test for Diagnosis of Schizophrenia

Partnership gives RBM exclusive rights to market and sell diagnostic test worldwide

AUSTIN, TX (June 11, 2008) — Rules-Based Medicine, Inc. (RBM), the leading multiplexed biomarker testing laboratory, announced today that it is partnering with Psynova Neurotech to co-develop and commercialize a blood test for the diagnosis of schizophrenia. RBM and Psynova will focus on the unmet clinical need for an objective and reliable diagnostic test to accelerate and optimize the treatment of schizophrenia. Under the terms of the agreement, the companies will collaborate on the validation, regulatory approval and manufacture of a diagnostic blood test for schizophrenia that will be sold worldwide exclusively by RBM.


Rules-Based Medicine Partners with EMD to Develop and Distribute Multi-Analyte Kits

Pharmaceutical, biotechnology and academic labs to gain access to the industry’s largest catalog of quantitative protein multiplex assays

AUSTIN, TX (December 10, 2007) — Rules-Based Medicine, Inc. (RBM), the leading multiplexed biomarker testing laboratory for the life sciences industry, announced today that it is partnering with the Novagen brand of EMD Chemicals Inc. (EMD), a subsidiary of Merck KGaA (Merck) of Germany, to develop and distribute high-quality immunoassay products on the Luminex® xMAP® platform. Under the terms of the agreement, RBM is granting EMD/Merck exclusive distribution rights to the largest catalog of quantitative protein multiplex assays currently available.


Rules-Based Medicine Raises $25 Million in Series A Funding

Equity Group Investments leads round, joined by Cross Creek Capital and Stephens Capital Partners; Matt Zell named to Board of Directors

AUSTIN, TX (October 15, 2007) — Rules-Based Medicine, Inc. (RBM), the leading multiplexed biomarker testing laboratory, announced today that it has raised $25 million in private financing. Equity Group Investments LLC (EGI), an investment fund founded by Sam Zell, led the Series A investment round. EGI is joined by Cross Creek Capital, the private equity affiliate of Wasatch Advisors, Inc. and Stephens Capital Partners. The financing will provide growth capital, debt repayment, and funding for acquisitions and investments to discover and validate biomarkers for medical diagnostics. In conjunction with the funding, RBM also announced that Matt Zell, managing director of EGI, has joined its Board of Directors.


Rules-Based Medicine Awarded $849,000 Grant by the National Institutes of Health

AUSTIN, Texas—(BUSINESS WIRE)—November 15, 2007—Rules-Based Medicine, Inc. (RBM) announced today that the National Institutes of Health has awarded RBM a "Fast-Track" grant for the development of a diagnostic test for neonatal sepsis. The grant, entitled "Biomarker Profiles for Early Diagnosis of Sepsis in Neonates," utilizes RBM’ s HumanMAP ® platform to characterize and validate a pattern of biomarkers that can detect early signs of infection in newborns. This project will be performed in collaboration with the University of New Mexico (UNM) in Albuquerque.


National Cancer Institute Awards $1.1 Million SBIR Contract to Rules-Based Medicine, Inc.

Goals of Funding are Earlier Detection and Better Characterization of Cancer

AUSTIN (October 10, 2007) — Rules-Based Medicine, Inc. (RBM), the leading multiplexed biomarker testing laboratory for the life sciences industry, announced today that the National Cancer Institute (NCI) has awarded the company a Phase I/Phase II "Fast-Track" Small Business Innovation Research (SBIR) Contract valued at $1,126,627. The contract will fund the development of 50 new quantitative, multiplexed immunoassays for cancer-related proteins to be added to the automated RBM Human Multi-Analyte Profile (HumanMAP®) platform. With the addition of these tests, RBM’s HumanMAP® will be expanded to more than 100 quantitative immunoassays for cancer biomarkers (as part of an existing panel of nearly 300 immunoassays) available for fast, sensitive, reproducible and cost-effective use by the worldwide community of cancer researchers.


Rules-Based Medicine Merges with EDI GmbH

Acquisition to benefit pharmaceutical, biotechnology and consumer products industries with comprehensive ex vivo biomarker testing platforms to aid pre-clinical and clinical research

AUSTIN, TX (October 9, 2007) — Rules-Based Medicine, Inc. (RBM), the leading multiplexed biomarker testing laboratory for the life sciences industry, announced today that it has acquired Experimentelle and Diagnostische Immunologie, GmbH, (EDI) in Reutlingen, Germany, an innovative developer of human organotypic (HOT) cell culture test systems. This transaction leverages the strong synergies between EDI’s HOT cultures and RBM’s Multi-Analyte Profiling (MAP) biomarker testing services. Researchers in the pharmaceutical, biotechnology and consumer products industries will benefit from these comprehensive ex vivo biomarker testing platforms, which will help bring safer products to market faster and at a lower cost. Terms of the agreement were not disclosed.


Rules-Based Medicine Awarded Phase II STTR Contract by U.S. Department of Defense

Austin, Texas, February, 2007 — Rules-Based Medicine, Inc. (RBM), the leading multiplexed biomarker testing laboratory for the life sciences industry, announced today that it has been awarded a Phase II Small Business Technology Transfer (STTR) grant by the United States Department of Defense entitled "Rapid Assessment of Individual Soldier Operational Readiness."


Changing Game Plan for Protein Profiling

January 1, 2007 — Genetic Engineering News & Biotechnology. Volume 27, Number 1. “The Changing Game Plan for Protein Profiling”. Integrated approaches are becoming the standard paradigm for proteomic studies. The "Multiplex Protein Biomarker Profiling” subsection highlights RBM’s capabilities including analyte menu expansion strategy and technology advantages.


Rules-Based Medicine and Multiplex Biosciences Merge

Merger extends R&D capabilities and product expertise; expands customer base

AUSTIN (November 15, 2006) — Rules-Based Medicine, Inc. (RBM), the leading multiplexed biomarker testing laboratory for the life sciences industry, announced today that it has merged with Lake Placid, New York-based Multiplex Biosciences, Inc. to extend its research and development capability in multiplexed assay product development and expand its customer base.